Our Journey to Understanding Mitochondria and Their Role in Preventing Symptoms and Miscarriages.
- ascension autism
- Mar 13
- 5 min read
Introduction to understanding Autism
Back in 2020, after joining HarvardX’s online Cellular Biology course led by Professor Robert A. Lue, we uncovered a groundbreaking truth: Mitochondrial diseases can be prevented by raising mitochondrial levels before pregnancy. This realization reshaped our entire approach to health, particularly for women and future generations.
Key Facts from Dr. Richard E. Frye’s Research on Autism Spectrum Disorder (ASD)
Personalized & Multidisciplinary Approach:
Dr. Frye emphasizes treating ASD through a tailored medical approach, addressing multiple organ systems such as the brain, immune system, and gastrointestinal system.
A combination of clinical history and biomarker analysis is used to create individualized treatment plans.
Treating ASD with Tetrahydrobiopterin (BH4):
In a 2010 study, Dr. Frye explored BH4 supplementation, a key cofactor for neurotransmitter production.
Results showed potential improvements in ASD symptoms, suggesting targeted biochemical therapies may be beneficial.
Biological Basis of Social Skills Deficits:
His 2018 review examined the neurobiological roots of social challenges in ASD.
Research explored the development of therapeutic agents to address these deficits, highlighting the role of brain function in social behavior.
Holistic ASD Treatment Model:
Dr. Frye advocates for a comprehensive treatment plan that includes medical, environmental, and dietary factors.
His approach aims to improve overall function and quality of life for individuals with ASD by addressing treatable medical conditions.
The link above Roberts interview during covid for unline learning
Through Professor Lue’s workshops, one key insight stood out—miscarriages are often linked to mitochondrial dysfunction. Yet, this critical information remains largely unknown to the public.
If mitochondria—the energy powerhouses of our cells—aren't functioning optimally, it can affect fertility, fetal development, and even contribute to the risk of passing on mitochondrial diseases to our daughters.
We began to ask ourselves: Why is this not common knowledge? Why aren’t we teaching this in schools?
"Reviewing PubMed studies can help you build understanding, even if you don’t grasp every word at first. Over time, both you and your mentees will absorb the information subconsciously, and the pieces of the puzzle will gradually come together."
Key Facts for Families on Female Health & Mitochondrial Function
1. The Importance of Female Health Education
Understanding simple health hacks and supplements can prevent mitochondrial diseases and reduce miscarriage risks.
Stem cells play a crucial role in maintaining overall female reproductive health.
Early education on these topics can empower young girls to make informed health choices.
2. The Impact of Misinformation & Stress
Many sources rely on buzzwords rather than real, actionable advice, leading to confusion and disappointment.
Parents experiencing stress and anxiety ("fight or flight" mode) struggle to make the best health decisions for their daughters.
Knowledge and preparation reduce stress and improve health outcomes.
3. Setting Higher Standards for Health Awareness
Families must recognize health problems and actively seek solutions.
Open discussions about health and biological processes are essential for young girls.
Educating daughters about their health equips them to handle future challenges confidently
4. Creating a Supportive Community for Better Health
Prioritizing education leads to better health for future generations.
Misinformation and fear should be replaced with awareness, hope, and real strategies.
Encouraging informed decision-making ensures that women can take control of their reproductive and mitochondrial health.
Mitochondria are essential components within our cells, often referred to as the cell's "powerhouses," as they generate the energy necessary for various bodily functions. Proper mitochondrial function is crucial during pregnancy for the healthy development of the fetus.
Key Points:
Role in Development: Mitochondria regulate energy and metabolism, influencing cell development and overall health. Disruptions in mitochondrial function can negatively impact pregnancy outcomes.
Mitochondrial Diseases (MDs): These are genetic disorders resulting from mutations in either nuclear DNA (nDNA) or mitochondrial DNA (mtDNA). MDs can affect various organs and systems, given mitochondria's presence in nearly all cell types.
Impact on Pregnancy: Severe mitochondrial dysfunction can lead to significant developmental issues or may be incompatible with life. This underscores the importance of proper mitochondrial function during embryonic and fetal development.
Clinical Observations: While much of the understanding comes from preclinical models, there is evidence suggesting that MDs can affect fetal development. Recognizing maternal and fetal outcomes associated with MDs is essential for timely genetic diagnosis and intervention.
Implications for Parents:
Understanding the role of mitochondria in pregnancy highlights the importance of genetic counseling and early detection of potential mitochondrial dysfunctions. This knowledge can lead to better management strategies during pregnancy, ensuring both maternal and fetal health.
For a more detailed exploration of this topic, you can refer to the full article:
Our families need to understand how mitochondrial diseases,
which are fundamentally viewed as genetic disorders, and the newly identified mitochondrial conditions are intricately related to one another.
It is crucial to recognize that these diseases stem from dysfunctions within the mitochondria, the powerhouses of our cells, which play a vital role in energy production and overall cellular health.
Many may not realize that every single illness and disease can be traced back to the mitochondria lacking essential biochemical compounds that are influenced by the microbiome.
This connection is especially significant when considering maternal health before and during pregnancy.
If a mother does not maintain high levels of mitochondrial function and health before conception and throughout her pregnancy, it can lead to serious consequences for the developing fetus.
This is a critical period when babies are formed, and any deficiencies in mitochondrial health can result in the production of faulty proteins. Such defects can manifest as visible deformities, missing limbs, or sensory impairments such as blindness and deafness.
Tragically, many infants born with severe mitochondrial dysfunction do not survive past the age of two, highlighting the urgent need for education and awareness regarding these conditions.
Furthermore, the relationship between autism and these mitochondrial diseases is a complex one.
Autism should not be viewed merely as a separate issue or condition but rather as a manifestation of underlying mitochondrial dysfunctions and other biochemical imbalances.
This perspective suggests that we have the potential to regenerate and repair damaged cells within the body.
While it is possible to improve symptoms associated with autism and other related conditions, it is essential to conduct research that focuses on identifying specific bacteria that may be missing from an individual's microbiome.
By understanding these microbial deficiencies, we can explore avenues for rebuilding not only muscle and tendon strength but also enhancing overall cellular function.
This includes optimizing bone density and performance through targeted therapies that stimulate mitochondrial production and enhance cellular health.
By addressing these foundational issues, we can work towards more effective treatments and improved quality of life for those affected by mitochondrial diseases and related disorders.
A Mission for Future Generations
We believe education is prevention. If young women and men understand how mitochondrial health impacts fertility and disease before they start families, they can make informed choices. If we can introduce conscious mitochondrial health education into schools, we can break the cycle—so our daughters don’t have to go through what so many women before them have endured.
If we fail to learn from the past, how can we build a better future for all our children and families?
The Science Behind Mitochondrial Health
Mitochondria and Fertility: Studies confirm that mitochondrial function declines with age, affecting egg quality and increasing miscarriage risk. (Nature)
Preventing Mitochondrial Diseases: Research shows that increasing mitochondrial function through proper nutrition, lifestyle, and potential medical interventions can reduce the risk of inherited disorders. (Cell Metabolism)
Mother-to-Daughter Inheritance: Mitochondria are passed down exclusively from mothers, meaning dysfunction can be carried across generations unless addressed. (National Library of Medicine)
Our journey started with a personal discovery, but it has become a mission. By raising awareness, we hope to create a future where mitochondrial health is prioritized—not just in medical circles but in everyday education, ensuring a healthier world for generations to come.
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